Medroxy Injection (10's Pack)
SKU: PHLO
Brand: Popular Pharmaceuticals Ltd.
৳450
৳480
Variant:
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Medroxy Inj similar to the progesterone hormone naturally produced by the body. It helps in regulating the periods, stop irregular bleeding, and for withdrawal bleeding in case of amenorrhea (unusual stopping of menstrual periods). Medroxy Inj should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include headache, abdominal pain, weakness, and dizziness. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. It may also cause irregular periods, bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently. Before taking this medicine you must let your doctor know if you ever had any problems like bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine.
Uses of Medroxy Inj
- Abnormal uterine bleeding
- Amenorrhea
Side effects of Medroxy Inj
Common
- Headache
- Abdominal pain
- Weakness
- Dizziness
- Irregular menstrual cycle
- Nervousness
How to use Medroxy Inj
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Medroxy Inj may be taken with or without food, but it is better to take it at a fixed time.
How Medroxy Inj works
Medroxy Inj is a progestin (female hormone). It works by replacing the natural progesterone hormone that the body is unable to make. This treats painful, irregular or absent menstrual periods. It also prevents an overgrowth of the lining of the uterus in menopausal women taking oestrogen (another female hormone).
Quick Tips
- Medroxy Inj is used for a wide range of menstrual disorders such as heavy, painful or absent periods, and endometriosis.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Stop taking Medroxy Inj and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, pain on breathing, sudden changes in your vision or hearing, or yellowing of your skin or whites of your eyes.
- Use a non-hormonal method of contraception such as condoms to prevent pregnancy while you are taking this medication.
- Do not take Medroxy Inj if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.
Brief Description
Indication
Menorrhagia, endometriosis, secondary amenorrhoea, contraception, abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology
Administration
May be taken with or without food. Incidence of minor indigestion may increase as dose increases. Take w/ meals if necessary.
Adult Dose
Oral Amenorrhea, Uterine Bleeding Uterine bleeding: 5-10 mg/day PO for 5-10 days; beginning day 16 or 21 of the menstrual cycle; withdrawal bleeding may be expected within 3 to 7 days after discontinuing medroxyprogesterone Amenorrhea, secondary: 5-10 mg/day PO for 5-10 days; may be started at any time; withdrawal bleeding may be expected within 3-7 days after discontinuing medroxyprogesterone Reduction of endometrial hyperplasia: 5 or 10 mg daily for 12 to 14 consecutive days per month, in postmenopausal women receiving daily 0.625 mg conjugated estrogens, either beginning on the 1st day of the cycle or the 16th day of the cycle. Endometriosis: 10 mg three times a day for 90 consecutive days, beginning on the first day of the menstrual cycle Intramuscular Contraception 150 mg deep IM every 3 months The initial injection should be given during the first 5 days after the onset of a normal menstrual period; within 5 days post-partum if not breast-feeding; or if exclusively breast-feeding at or after six weeks post-partum.
Contraindication
Thromboembolic disorders; cerebral apoplexy; severe hepatic dysfunction; incomplete abortion, hormone-dependent carcinoma; Undiagnosed vaginal bleeding, Undiagnosed urinary tract bleeding, Known or suspected pregnancy, Undiagnosed breast pathology, Missed abortion, Active thromboembolic disorders, Markedly impaired liver function,
Mode of Action
Medroxyprogesterone is a synthetic progestogen which converts the proliferative phase of the endometrium into secretory phase. It has some androgenic and anabolic activities but no oestrogenic effects. Parenteral use leads to inhibition of pituitary gonadotropins, thus preventing follicular maturation and ovulation.
Precaution
Breakthrough bleeding is likely to occur in patients being treated for endometriosis. May cause some degree of fluid retention, conditions which might be influenced by this factor, such as epilepsy, migraine, asthma, or cardiac or renal dysfunction, require careful observation. A decrease in glucose tolerance has been observed in some patients. Patients with depression, DM, epilepsy, asthma, migraine, hypertension, renal or cardiac dysfunction. Monitor patient closely for loss of vision, proptosis, diplopia and thromboembolic disorders. Lactation: Safe
Side Effect
>10% Amenorrhea,Breakthrough bleeding,Change in menstrual flow,Spotting,Edema,Anorexia,Weakness,Pain at injection site Frequency Not Defined Angioedema,Change in weight,Depression,Dizziness,Headache,Nervousness,Somnolence,Breast tenderness,Galactorrhea,Abdominal pain,Nausea and vomiting,Cholestatic jaundice,Deep vein thrombosis (DVT),Thrombophlebitis Potentially Fatal: Thrombophlebitis and pulmonary embolism.
Interaction
Aminoglutethimide and enzyme-inducing drugs (e.g. carbamazepine, griseofulvin, phenobarbital, rifampicin, phenytoin) may reduce plasma concentrations leading to reduced efficacy. Additional measures required when medroxyprogesterone is used for contraception during coadministration with these drugs.
