Alpha-lipoic acid is an antioxidant that is made naturally in the body and found in foods. It is used to break down carbohydrates and to make energy. Alpha-lipoic acid can be eaten in foods, such as red meat, carrots, beets, spinach, broccoli, and potatoes. It is also available in supplements. Because alpha-lipoic acid seems to work like an antioxidant, it might provide protection to the brain. People most commonly use a -lipoic acid for nerve pain in people with diabetes. It is also used for obesity, altitude sickness, aging skin, high levels of cholesterol or other fats in the blood, and many other purposes.
Alpha-lipoic acid is a substance that can be naturally found in animal and plant tissues and maintains its activity both in aqueous cell compartments and in lipid membrane ones. Alpha-lipoic acid has multiple antioxidant mechanisms, including metal chelating, regenerating endogenous antioxidants such as vitamins C and E, and modulating several signaling pathways, Alpha-lipoic acid plays a significant role in managing peripheral neuropathy, particularly diabetic neuropathy, Alpha-lipoic acid can pass easily into the brain, it may help protect the brain and nerve tissue, a-lipoic acid helps lower blood sugar levels. Its ability to kill free radicals may help people with diabetic peripheral neuropathy, who have pain, burning, itching, tingling, and numbness in arms and legs from nerve damage, Alpha-lipoic acid has been found to reduce the expression of GLUT~4s (Glucose transporter type 4) in cells, responsible for glucose uptake, and hence reduce Insulin sensitivity.